If you’re considering Biote Pellet Therapy or have just received your first insertion, you may be wondering what the next few weeks will feel like. The first month is an important adjustment period—your body begins responding to consistent, bioidentical hormone levels delivered through tiny Biote pellets placed just beneath the skin. Understanding what to expect can help you feel confident, prepared, and excited about the journey toward better hormone optimization.
At Drip Drop Health & Wellness PLLC, our goal is to guide you through every step of the process so you feel supported and informed from day one.
What Is Biote?
Biote is a leading method of bioidentical hormone replacement therapy (BHRT) that uses plant-derived hormones formulated to closely match the hormones your body naturally produces. Unlike creams, pills, or injections, Biote hormone pellets provide a steady, consistent release of hormones over several months. This helps minimize the roller-coaster effect some patients experience with other delivery methods.
What Are Biote Pellets and How Do They Work?
Biote pellets are about the size of a grain of rice and contain either estrogen or testosterone. They are inserted subcutaneously—usually in the hip area—through a quick in-office procedure. Once placed, your body gradually absorbs the pellet as needed, stabilizing hormone levels in a way that feels natural and steady.
This steady release is one of the reasons patients often prefer pellets over other BHRT options. It reduces the peaks and valleys that accompany oral or topical hormone therapy and offers sustained support for energy, mood, metabolism, libido, and cognitive clarity.
Week 1: Immediate Post-Procedure Expectations
During your first week on Biote Pellet Therapy, your body is adjusting to the initial release of hormones.
What You May Feel
-
Tenderness or swelling at the insertion site
-
Mild bruising that improves within several days
-
Increased energy or improved mood, depending on your hormone levels before treatment
-
Little to no symptom change, which is also normal early on
Every patient is different. Some notice changes quickly, while others need more time as hormone levels begin to stabilize.
Activity Guidelines
To ensure the pellet stays in place and heals properly:
-
Avoid lower-body workouts for 3–5 days.
-
Keep the area clean and dry for 24 hours.
-
Do not submerge the area in water (pools, hot tubs, baths) for several days.
Your provider will give you personalized instructions based on your procedure.
Week 2: Subtle Shifts and Early Improvements
As your hormones begin to regulate, many patients start noticing subtle but encouraging changes.
Common Experiences This Week
-
More consistent energy levels
-
Slight improvements in sleep
-
Reduced brain fog
-
Early signs of libido enhancement
-
Beginning relief from menopausal or andropausal symptoms
You may also notice emotional balancing—less irritability, fewer mood swings, and a steadier sense of well-being.
These improvements typically happen gradually, not all at once.
Week 3: Hormone Optimization Begins
By week three, pellets have usually reached a more stable release pattern.
What Many Patients Report
-
Noticeable improvements in motivation and mental clarity
-
Better, more restorative sleep cycles
-
More consistent mood stability
-
Enhanced sexual function and libido
-
A decrease in hot flashes or night sweats
-
Improved concentration and memory recall
For some, this is the week when everything “clicks.” Others continue progressing at a more gradual pace—which is completely normal.
Week 4: Feeling the Full Benefits of Biote Pellet Therapy
By the end of the first month, many patients experience the true benefits of hormone optimization.
Common Month-One Benefits
-
Increased vitality
-
More balanced emotions
-
Better stress resilience
-
Stabilized metabolism and easier weight management
-
Significantly improved sleep quality
-
Renewed sexual wellness
-
Clearer thinking and improved focus
If you’ve struggled with hormone-related symptoms for a long time, the steady improvement during this phase often feels life-changing.
Are Biote Supplements Needed During the First Month?
Many providers recommend supportive Biote supplements to help your body metabolize hormones efficiently and enhance symptom relief. These may include supplements targeting inflammation, nutrient support, adrenal function, or detoxification pathways.
Although not required for every patient, supplements can maximize results and help maintain long-term hormone balance. Your provider will review your lab work and symptoms before making personalized recommendations.
Common Questions About Your First Month
How soon will I feel results?
Some patients feel better within days, while others need 3–4 weeks to experience noticeable changes. Your pre-pellet hormone levels, health history, and metabolism all play a role.
Will I have side effects?
Temporary changes can occur as your body adjusts, including:
-
Mild acne
-
Breast tenderness
-
Water retention
-
Mood fluctuations
These effects usually fade as levels stabilize.
How long do Biote pellets last?
Most pellets last 3–5 months for women and 4–6 months for men. Your body absorbs the pellet at its own pace, depending on factors like activity level and metabolism.
When to Follow Up With Your Provider
Drip Drop Health & Wellness PLLC schedules a follow-up around 4–6 weeks after your first insertion. This allows your provider to:
-
Evaluate how your body is responding
-
Review your symptom improvements
-
Check hormone levels
-
Adjust dosing if needed
This early follow-up is one of the keys to achieving optimal results with Biote Pellet Therapy.
How Drip Drop Health & Wellness PLLC Supports Your Hormone Journey
Choosing pellet therapy is a major step toward feeling better, and your provider’s expertise matters. At Drip Drop Health & Wellness PLLC, you can expect:
A Personalized Treatment Plan
Your hormone therapy is never one-size-fits-all. Your provider tailors your pellet dose based on comprehensive lab testing, symptoms, and personal wellness goals.
Education & Ongoing Guidance
You’ll receive clear instructions, expectations, and guidance so you know exactly what to expect during each stage of treatment.
Whole-Body Wellness Support
Because hormone health affects every system in the body, your provider also evaluates lifestyle factors such as sleep, stress, nutrition, and movement—offering additional support when needed.
Your First Month Is the Start of a Healthier, More Energized You
Your first month on Biote Pellet Therapy is a journey of gradual improvement as your body adapts to balanced hormones. From subtle energy shifts to powerful changes in mood, sleep, libido, and mental clarity, pellet therapy offers a natural, steady path toward hormone optimization.
If you're ready to feel more energized, balanced, and in control of your health, the team at Drip Drop Health & Wellness PLLC is here to guide you through every step of the process.
